Adriana Cangelosi Selected Research

Shiga Toxin 2

2/2019	Shiga toxin 2 from enterohemorrhagic Escherichia coli induces reactive glial cells and neurovascular disarrangements including edema and lipid peroxidation in the murine brain hippocampus.
12/2018	Anti-inflammatory agents reduce microglial response, demyelinating process and neuronal toxin uptake in a model of encephalopathy produced by Shiga Toxin 2.
1/2017	Dexamethasone prevents motor deficits and neurovascular damage produced by shiga toxin 2 and lipopolysaccharide in the mouse striatum.
1/2013	Dexamethasone rescues neurovascular unit integrity from cell damage caused by systemic administration of shiga toxin 2 and lipopolysaccharide in mice motor cortex.
1/2013	A translational murine model of sub-lethal intoxication with Shiga toxin 2 reveals novel ultrastructural findings in the brain striatum.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Adriana Cangelosi Research Topics

Disease

3	Brain Diseases (Brain Disorder) 02/2019 - 01/2013
3	Hemolytic-Uremic Syndrome 02/2019 - 01/2013
2	Infections 09/2022 - 01/2013
2	Diarrhea 02/2019 - 01/2017
1	Bites and Stings (Sting) 01/2021
1	Snake Bites (Snake Bite) 05/2019
1	Edema (Dropsy) 02/2019
1	Encephalomalacia 05/2017
1	Brain Edema (Cerebral Edema) 05/2017
1	Neurologic Manifestations (Neurological Manifestations) 01/2013
1	Colitis 01/2013

Drug/Important Bio-Agent (IBA)

5	Shiga Toxin 2IBA 02/2019 - 01/2013
2	Shiga Toxin (Shigella Toxin)IBA 09/2022 - 01/2013
2	Antivenins (Antivenoms)IBA 01/2021 - 05/2019
1	Virulence Factors (Pathogenicity Factors)IBA 09/2022
1	LipopolysaccharidesIBA 09/2022
1	Melitten (Melittin)IBA 01/2021
1	Bee Venoms (Bee Venom)IBA 01/2021
1	Phospholipases A2 (Phospholipase A2)IBA 01/2021
1	Complex MixturesIBA 01/2021
1	IgYIBA 01/2021
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 12/2018
1	Clostridium perfringens epsilon-toxinIBA 05/2017
1	Pharmaceutical PreparationsIBA 01/2013
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2013

Therapy/Procedure

1	Intravenous Administration 01/2013